Robert Lustig: THIS Is Why You Can’t Lose Body FAT… (Not Calories) | The Glucose Expert Robert Lustig

• It’s not about calorie
• Calorie is determined by Bomb Calorimeter
• This is a MEASURE OF HEAT
• But the BODY is not a MEASURE OF HEAT

• We BURN inside MITOCHONDRIA.
• Burn that FOOD to generate ATP

• Glucose STIMULATES mitochondria to work better: AMP kinese HADH hydroxyacyl-CoA dehydrogenase

• Fructose INHIBITS mitochondria: AMP, CPT1, and another one.

• So – FRUCTOSE has CALORIES (so yea, it can burn and raise the temperature of water) BUT it actually INHIBITS Mitochondria.
• This is the key point about why all calories are not the same!

• Think in terms of Macros, and not in Calories

• Insulin blocks Leptin.
• Leptin controls set point

Get the Insulin down

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